Izzo made his professional debut for Adelaide United in 2012. He was released by Adelaide United on 8 July 2015, and subsequently signed with the Central Coast Mariners for two years. In April 2017, Izzo returned to hometown club Adelaide United on a three-year contract, before being transferred to Greek club Xanthi for an undisclosed fee, following a few Australian players and coach Tony Popovic, in October 2020. Izzo represented Australia at U20 level at the 2012 AFC U-19 Championship in United Arab Emirates and was first called up for the senior Socceroos squad on the 28th of August 2021, for world cup qualifiers against China and Vietnam. He is a new addition to the ONE Family, after joining us in July 2023.